What is Dihydrostreptomycin sulfate?

Dihydrostreptomycin sulfate is an aminoglycoside antibiotic derived from streptomycin. It is widely used in veterinary medicine to treat bacterial infections, particularly those caused by Gram-negative bacteria. This powder formulation offers convenience for administration in animals, ensuring effective treatment against susceptible pathogens.

Chemical Properties

Dihydrostreptomycin sulfate is a white or almost white, crystalline powder that is highly soluble in water but insoluble in organic solvents. Its chemical structure is similar to streptomycin but with a saturated dihydrostreptose moiety, enhancing its stability and antimicrobial activity.

Mechanism of Action

Like other aminoglycosides, dihydrostreptomycin sulphate works by binding to the 30S subunit of bacterial ribosomes, inhibiting protein synthesis. This bactericidal effect is concentration-dependent, making it effective against rapidly multiplying bacteria.

Veterinary Applications

Treatment of Infections – Used for respiratory, urinary, and gastrointestinal infections in livestock, poultry, and pets.

Combination Therapy – Often combined with penicillin (e.g., procaine penicillin) to broaden antibacterial coverage.

Prophylactic Use – Sometimes administered to prevent bacterial infections in high-risk environments.

Administration and Dosage

Dihydrostreptomycin sulfate powder is typically administered via:

Oral route (mixed with feed or water)

Intramuscular injection (after reconstitution)

Dosage varies depending on the animal species, weight, and infection severity. Veterinary guidance is essential to avoid toxicity.

Safety and Side Effects

While effective, dihydrostreptomycin sulfate can cause:

Ototoxicity (damage to auditory nerves)

Nephrotoxicity (kidney damage)

Neuromuscular blockade (rare but severe)

It is contraindicated in animals with pre-existing kidney or hearing disorders.

Regulatory Status

Due to concerns about antibiotic resistance, its use is restricted in some countries. Proper withdrawal periods must be observed in food-producing animals to prevent residual antibiotic presence in meat and milk.

Where to buy Dihydrostreptomycin sulfate?

Our Lifeworth is a professional supplier & manufacturer for Dihydrostreptomycin sulfate,our company has passed GMP certification and EU CEP certification, and some products have passed German EU-GMP certification, US FDA certification, and sterile CEP certification.Our company has 7 production lines dedicated to the production of pure Dihydrostreptomycin sulfate, we can supply 99% pure BP EP USP Dihydrostreptomycin sulfate powder,with an annual output of more than 11,500 tons of pure Dihydrostreptomycin sulfate.The product has been exported to more than 80 countries around the world, including North America, Europe, Asia, South Africa, etc.,the product quality has always been recognized by customers.

In addition to pure Dihydrostreptomycin sulfate powder,we also can supply pure ciprofloxacin lactate powder,pure Ciprofloxacin Hydrochloride powder,USP BP Amoxicillin Trihydrate Powder, 99% pure ampicillin, ampicillin sodium, erythromycin, penicillin powder, azithromycin and other products. The quality of our products meets the BP EP USP standard, and the annual output of antibiotic products exceeds 80,000 tons. Our production capacity and product quality are stable, and our product prices are competitive in the market. Our products have a great influence in the international market.

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Conclusion

Dihydrostreptomycin sulfate powder remains a valuable tool in veterinary medicine for combating bacterial infections. However, responsible use under professional supervision is crucial to minimize resistance and adverse effects.Reference:

https://pubchem.ncbi.nlm.nih.gov/compound/Dihydrostreptomycin-Sulfate

Package:

1.1-5kg sample order we can provide aluminum foil bag package.

2.5-10kg order we can provide aluminum foil bag package.

3.Normally a full packge is 25kg/drum or 25kg/bag or 25kg/carton.

Contacts:

E-Mail: sales@naturallifeworth.com
Mobile: 0086-18292562757
Whatsapp: 0086-18292562757