Dihydroberberine Powder
Lifeworth supplies dihydroberberine powder for supplement manufacturers, nutraceutical brands, ingredient distributors, and functional nutrition projects. We support specification review, sample evaluation, COA, SDS/MSDS, and flexible bulk packaging for international sourcing.
• Dihydroberberine powder with CAS 483-15-8 identification
• Assay options available according to project requirements
• HPLC testing and batch COA documentation support
• Suitable for supplement, capsule, tablet, and functional nutrition formulations
• Sample evaluation, bulk packaging, and export documentation available
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.
Quick Specs
Identity
INCI Name
Alias
CAS Number
Molecular Formula
Molecular Weight
Quality
Assay
Grade
Standards
Assay Method
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
Dihydroberberine Powder is a specialty berberine-derived ingredient commonly evaluated for advanced dietary supplement and functional nutrition formulations.
It is usually supplied as a yellow to brownish yellow powder, and buyers often review HPLC assay, CAS number, impurity profile, residual solvents, heavy metals, microbial limits, and documentation scope before technical or commercial evaluation.
It is commonly considered for capsule, tablet, and functional supplement formulations, with sample supply and batch documentation available for sourcing evaluation.
Applications
Dietary Supplements
Dihydroberberine powder is commonly used in dietary supplement capsules and tablets, including advanced berberine-related formulations and differentiated functional ingredient programs. It is suitable for brands seeking a specialty berberine-derived ingredient with clear specification and documentation support.
Functional Nutrition Formulas
Dihydroberberine can be used in functional nutrition formulas, powder blends, and specialty supplement systems. Because the ingredient is typically used at controlled dosage levels, formulators should review blending uniformity, color impact, excipient compatibility, and finished-product stability during development.
Berberine Alternative Formulas
Dihydroberberine is often selected by brands looking to differentiate from standard berberine HCl formulas. Buyers should compare chemical form, assay basis, supplier documentation, dosage target, and label declaration before commercial launch.
Capsule and Tablet Manufacturing
For capsule and tablet production, dihydroberberine powder should be evaluated for particle size, flowability, bulk density, uniform blending, and compatibility with excipients. Pilot testing is recommended before large-scale filling or compression.
How to Choose the Right Grade / Form
Standard Supplement Grade
For general dietary supplement capsules and tablets, 97% or 98% dihydroberberine powder by HPLC is commonly considered. This grade is suitable for brands that need a clear active ingredient specification and routine batch documentation.
High-Assay Grade
For premium formulas or stricter internal quality standards, buyers may prefer 99% assay by HPLC. In this case, impurity profile, residual solvents, heavy metals, microbial limits, and batch consistency should be reviewed together with assay.
Formula Development Grade
For new product development, buyers should choose a grade that matches the target dosage form, blending process, capsule size, tablet design, and finished-product stability requirement. Sample testing is recommended before commercial order confirmation.
Documentation-Focused Grade
For export or regulated supplement projects, the selected grade should be supported by COA, SDS/MSDS, TDS, allergen statement, GMO statement, heavy metal information, and other documents required by the destination market.
Confirm the Assay Basis
The first specification point is assay by HPLC. Buyers should confirm whether the assay is calculated as dihydroberberine content and whether the method is suitable for internal quality review and supplier comparison.
Confirm Berberine-Related Impurities
Because dihydroberberine is a berberine-related ingredient, buyers should review related substances and conversion-related impurities carefully. A clear impurity profile helps reduce quality risk during formulation and supplier qualification.
Confirm Destination-Market Fit
Dihydroberberine may be treated differently across markets depending on intended use, labeling, dosage, and product category. Buyers should confirm local supplement regulations, import requirements, and label claims before commercial launch.
Technical & Formulation Notes
Technical Notes
Dihydroberberine is commonly positioned as a next-generation berberine-related ingredient for supplement formulations.
For procurement review, buyers should confirm CAS 483-15-8, assay by HPLC, appearance, identification, impurity profile, residual solvents, heavy metals, and microbial limits before order confirmation.
Manufacturing & Process
Commercial dihydroberberine powder is typically produced through controlled conversion, purification, drying, and particle-size adjustment processes.
Batch consistency should be evaluated through HPLC assay, identification, moisture or loss on drying, related substances, and microbiological testing according to the agreed specification.
Compatibility / Formulation Notes
For capsules and tablets, dihydroberberine powder should be blended carefully because it is usually used at relatively low dosage levels. Uniform distribution is important for finished-product consistency.
For powder blends, formulators should evaluate color impact, dispersion, moisture sensitivity, and compatibility with fibers, minerals, vitamins, sweeteners, and other functional ingredients.
For formulas replacing or upgrading standard berberine HCl, buyers should review dosage target, active basis, label declaration, and market-positioning language before launch.
Dihydroberberine powder should be protected from moisture, heat, and direct light during storage and processing. Opened packaging should be resealed quickly after use.
Pilot testing is recommended before commercial production, especially for tablets, stick packs, and complex multi-ingredient supplement formulas.
Extended QC & Test Items
Extended quality review may include appearance, identification, assay by HPLC, loss on drying, residue on ignition, related substances, residual solvents, heavy metals, lead, arsenic, cadmium, mercury, total plate count, yeast and mold, E. coli, and Salmonella.
For supplement projects, buyers should also review allergen, GMO, country-of-origin, and market-related compliance documents where required.
Product specifications
| Test | Specification | Method |
|---|---|---|
| Appearance | Yellow to brownish yellow powder | Visual |
| Identification | Conforms to reference standard | HPLC / IR |
| Assay | 97.0%, 98.0%, or 99.0% min | HPLC |
| Loss on Drying | Per agreed specification | USP / In-house |
| Residue on Ignition | Per agreed specification | USP / In-house |
| Related Substances | Per agreed specification | HPLC |
| Residual Solvents | Per agreed specification | GC |
| Heavy Metals | Per agreed specification | ICP-MS / AAS |
| Lead | Per agreed specification | ICP-MS / AAS |
| Arsenic | Per agreed specification | ICP-MS / AAS |
| Cadmium | Per agreed specification | ICP-MS / AAS |
| Mercury | Per agreed specification | ICP-MS / AAS |
| Total Plate Count | Per agreed specification | USP / ISO |
| Yeast & Mold | Per agreed specification | USP / ISO |
| E. coli | Negative | USP / ISO |
| Salmonella | Negative | USP / ISO |
Storage, Shelf Life & Packaging
Storage
Store dihydroberberine powder in a tightly sealed container in a cool, dry, and well-ventilated place.
Protect the product from moisture, direct sunlight, high temperature, and prolonged air exposure during storage, handling, and transportation.
Shelf Life
Typical shelf life is 24 months when stored in unopened original packaging under recommended conditions.
The actual shelf life should be confirmed according to the batch COA, packaging format, and storage environment.
Packaging & Logistics
Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Lifeworth supports global buyers sourcing dihydroberberine powder with a focus on specification clarity, documentation readiness, and reliable ingredient supply.
We provide technical documents including COA, TDS, and SDS/MSDS for evaluation, together with batch information and packaging options according to project requirements.
For supplement manufacturers, nutraceutical brands, and ingredient distributors, we support sample evaluation, specification confirmation, and bulk supply planning to help streamline the sourcing process.
FAQ
What is dihydroberberine powder?
Dihydroberberine powder is a specialty berberine-derived ingredient commonly evaluated for dietary supplement and functional nutrition formulations. Buyers typically review assay, specification range, documentation package, and supplier qualification information before sourcing.
What assay specifications are available for dihydroberberine powder?
Dihydroberberine powder can be supplied according to different assay requirements based on project needs. Buyers should confirm the HPLC assay method, specification range, impurity profile, and supporting batch documentation before commercial evaluation.
What documents are available for bulk dihydroberberine powder supply?
Typical documents include COA, TDS, and SDS/MSDS. Additional quality documents or statements may be provided according to destination market requirements and customer qualification procedures.
What are the common applications of dihydroberberine powder?
Dihydroberberine powder is commonly used in dietary supplement capsules, tablets, powder blends, and functional nutrition formulations. Application suitability should be evaluated according to formulation requirements and finished-product specifications.
How is dihydroberberine different from berberine HCl?
Dihydroberberine and berberine HCl are different berberine-related chemical forms. Buyers comparing these ingredients should review chemical form, assay basis, formulation objectives, and quality requirements before selecting the appropriate ingredient.
Can I request a sample before placing a bulk order?
Yes. Sample evaluation is available for buyers who need to review product characteristics, specifications, and formulation compatibility before commercial purchasing.
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