Crospovidone / PVPP Powder (Crosslinked PVP)

For tablet disintegration, solid dosage formulation, and selected crosslinked polymer projects, with support for specification review, documentation, and bulk supply.

Crospovidone / PVPP Powder is a crosslinked PVP pharmaceutical excipient commonly selected for tablet disintegration and oral solid dosage formulations.

The product is evaluated according to disintegration performance, grade requirements, technical documentation, and commercial supply conditions.

• Suitable for tablet disintegration and oral solid dosage formulation applications

• Commonly evaluated as a crosslinked PVP pharmaceutical excipient with Type A and Type B grade options

• COA, SDS/MSDS, and TDS/specification sheet available on request

• Bulk packing and export support available

Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.

USP crospovidone PVPP powder polyvinylpyrrolidone crosslinking,bulk,supplier,manufacturer

Quick Specs

Identity

INCI Name

Crospovidone

Alias

Crospovidone; PVPP; Polyvinylpolypyrrolidone; Crosslinked PVP; Crospovidone Powder; Crospovidone Type A; Crospovidone Type B; Pharmaceutical Disintegrant; Tablet Disintegrant

CAS Number

25249-54-1

Molecular Formula

(C6H9NO)n

Molecular Weight

Crosslinked polymer; not expressed as a fixed single molecular weight

Quality

Assay

Per agreed specification / insoluble crosslinked polymer route

Grade

Food Grade, Pharm Grade

Standards

BP, USP, EP, FCC

Assay Method

HPLC

Handling

Appearance

White to off-white powder

Form

Powder

Solubility

Insoluble crosslinked PVP polymer; selected for tablet disintegration and related solid dosage formulation applications.

Applications

Tablet disintegration systems, oral solid dosage formulations, pharmaceutical excipient applications, and crosslinked PVP material sourcing projects.

Commercial Terms

MOQ

MOQ depends on packaging and specification.

Lead Time

3–7 working days for standard items; bulk orders by schedule.

Incoterms

EXW / FOB / CIF / DAP / DDP

Sample

Free sample (shipping charged)

Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.

Product Overview

Crospovidone / PVPP is a crosslinked PVP pharmaceutical excipient commonly selected for tablet disintegration, oral solid dosage formulation, and applications where insoluble polymer performance is required.

Unlike standard soluble PVP grades, crospovidone is typically evaluated according to crosslinked functionality, processing behavior, and formulation fit rather than viscosity-based grade selection.

It is commonly used in pharmaceutical formulation development and commercial manufacturing projects, with technical documentation and bulk supply support available for supplier evaluation.

USP crospovidone PVPP powder bulk

Applications

Tablet Disintegration Systems

Crospovidone / PVPP is widely used as a pharmaceutical disintegrant in tablet formulations where rapid liquid uptake, swelling behavior, and consistent disintegration performance are required.

Pharmaceutical Excipient Applications

Suitable for pharmaceutical formulation projects evaluating insoluble crosslinked PVP materials as part of oral solid dosage systems, including tablets and related excipient applications.

Type A / Type B Crospovidone Evaluation

Different crospovidone specifications, including Type A and Type B grades where available, may be considered according to particle characteristics, formulation requirements, and desired processing performance.

Commercial Bulk Supply

Suitable for manufacturers, distributors, and formulation developers requiring document-supported bulk sourcing of crospovidone / PVPP powder.

How to Choose the Right Grade / Form

Choose Crospovidone Type A when:

Your formulation requires a commonly used pharmaceutical disintegrant route with suitable particle characteristics, processing behavior, and specification requirements for tablet applications.

Choose Crospovidone Type B when:

Your project requires a different crospovidone specification profile and should be evaluated according to formulation design, processing conditions, and target disintegration performance.

Choose according to particle size and specification requirements:

Crospovidone grades may differ in particle characteristics, functional behavior, and specification range. Buyers should confirm the required grade, pharmacopeia standard, and application requirements before selection.

For pharmaceutical tablet projects:

Confirm dosage form, disintegration expectations, target market requirements, documentation needs, and packaging requirements before commercial sourcing.

Technical & Formulation Notes

Technical Notes

Crospovidone / PVPP is an insoluble crosslinked PVP material commonly evaluated as a pharmaceutical disintegrant for tablet and solid dosage applications.

Unlike soluble povidone grades, crospovidone is selected based on crosslinked structure, disintegration performance, particle characteristics, and specification requirements.

Commercial evaluation may include different crospovidone grades such as Type A or Type B according to available specifications, formulation requirements, and application objectives.

Crospovidone is produced through controlled polymerization and crosslinking processes to create an insoluble crosslinked PVP structure.

During commercial production, quality control focuses on consistent functional performance, particle characteristics, moisture control, and batch-to-batch specification stability.

Manufacturing documentation and quality information can be reviewed according to the required grade, application, and market requirements.

Crospovidone / PVPP selection is usually based on dosage form requirements, disintegration performance, particle characteristics, and formulation objectives rather than product name alone.

For tablet development and commercial production, buyers may review factors such as crospovidone grade, Type A or Type B classification where applicable, particle size, specification requirements, and documentation availability.

The final selection should be confirmed according to formulation design, manufacturing process, regulatory requirements, and target market expectations.

Crospovidone quality evaluation may include identification, appearance, moisture content, particle size distribution, functional performance, and other specification items according to the selected grade and application requirements.

Additional quality documentation such as COA, TDS, SDS, and regulatory-related documents can be reviewed for commercial sourcing projects.

Product specifications

TestSpecificationMethod
AppearanceWhite to off-white powderVisual
IdentificationConforms to agreed specificationPer specification
Swelling / Functional BasisReviewed according to agreed specificationPer specification
Loss on DryingPer agreed specificationPer specification
Heavy MetalsPer agreed specificationPer specification
DocumentsCOA per batch; SDS/MSDS and TDS availableReference

Storage, Shelf Life & Packaging

Storage

Store in a cool, dry place in tightly sealed containers.

Protect from moisture, contamination, and prolonged exposure during storage and transportation.

Shelf Life

Shelf life should follow the agreed specification and original packing condition.

Batch label, packaging integrity, and storage compliance should be checked before use.

Packaging & Logistics

Sample Packing
Small evaluation packs can be arranged for formulation review and supplier comparison.

Bulk Packing
Common supply formats may include 1 kg, 5 kg, 10 kg, 20 kg, and 25 kg export packing depending on project and shipment arrangement.

Customization
Custom pack size, labeling format, and selected supply configuration may be arranged according to product scope and market requirements.

Logistics & Documents
COA, SDS/MSDS, TDS/specification sheet, and related shipment-support documents can be arranged according to the agreed supply plan.

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Supply, Documentation & Customization

Documents & Compliance

COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.

Customization & Private Label

Custom packing, private label, and labeling support available depending on product type and order scope.

Commercial Support

Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.

Why Source From Lifeworth

Crospovidone sourcing support

Support for buyers evaluating crospovidone / PVPP powder based on disintegration requirements, formulation objectives, grade selection, and application suitability.

Specification-focused communication

We support technical and purchasing discussions around crospovidone specifications, including functional requirements, documentation review, packaging options, and commercial supply planning.

Quality documentation support

COA, SDS/MSDS, TDS, and related product documents can be provided for technical evaluation, quality review, and purchasing processes.

Export-oriented bulk supply

Packaging coordination, shipment support, and bulk supply arrangements are available for international pharmaceutical ingredient sourcing projects.

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FAQ

1. What is the difference between crospovidone and standard PVP?

Crospovidone is an insoluble crosslinked PVP material mainly used as a pharmaceutical disintegrant, while standard PVP / povidone grades are soluble polymer materials commonly used for binding, film-forming, and other excipient functions.

2. What is the difference between Crospovidone Type A and Type B?

Crospovidone Type A and Type B refer to different specification routes available for crospovidone materials. The suitable selection depends on formulation requirements, particle characteristics, processing conditions, and applicable product specifications.

3. What is crospovidone used for?

Crospovidone is commonly used as a pharmaceutical disintegrant in tablet and solid dosage formulations where rapid disintegration performance and consistent processing behavior are required.

4. How should buyers select the right crospovidone grade?

Buyers usually consider application requirements, pharmaceutical standard, particle size characteristics, specification range, documentation needs, and final dosage form before selecting a suitable crospovidone grade.

5. What documents are available for crospovidone?

COA per batch / lot is available. SDS/MSDS, TDS, specification sheets, and related technical documents can be provided according to project requirements.

6. Can crospovidone samples be arranged before bulk purchase?

Yes. Samples can be discussed for formulation evaluation, technical review, and supplier qualification before commercial orders.

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