Cyanocobalamin Powder
Lifeworth supplies high-purity cyanocobalamin powder for manufacturers, importers and distributors reviewing assay, applicable standard, packaging protection, batch documentation and commercial supply requirements.
- 99% high-purity cyanocobalamin powder
- USP-aligned or customer-agreed specifications
- Suitable for supplements, fortified foods and premixes
- Batch COA, SDS/MSDS and TDS support
- Sample evaluation, flexible packing and bulk supply
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.
Quick Specs
Identity
INCI Name
CAS Number
Molecular Formula
Molecular Weight
Quality
Assay
Grade
Standards
Assay Method
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
Cyanocobalamin powder is a commercially established vitamin B12 ingredient commonly used in dietary supplements, fortified foods, vitamin premixes and selected specification-driven formulations.
It is typically supplied as a high-purity dark red crystalline powder, and buyers usually review assay, applicable standard, impurity controls, packaging protection and batch consistency before technical or commercial evaluation.
It is commonly considered for tablets, capsules, gummies, powder blends and food-fortification systems, with sample evaluation, batch documentation and bulk supply support available for sourcing reference.
Applications
Dietary Supplements
Cyanocobalamin powder is commonly evaluated for tablets, capsules, gummies and multivitamin products requiring an established and commercially practical vitamin B12 form. Its controlled assay, broad commercial availability and cost-efficient positioning make it suitable for standard supplement lines and larger-scale formulation projects.
Food & Beverage Fortification
Cyanocobalamin may be considered for nutrition powders, cereal products, beverage premixes and other fortified food systems. The selected specification should match the finished-food category, processing conditions, dosage requirements and destination-market compliance needs.
Vitamin and Mineral Premixes
High-purity cyanocobalamin can be used as an input for customized vitamin and mineral premixes. Accurate low-dose weighing, suitable dilution and controlled premixing are important for supporting uniform distribution in commercial production batches.
Pharmaceutical-Oriented Formulations
Cyanocobalamin may also be evaluated for specification-driven pharmaceutical or professional formulation projects requiring defined test limits, batch consistency and supporting quality documentation. Final suitability should be reviewed by the customer’s technical, quality and regulatory teams.
How to Choose the Right Grade / Form
Confirm the Intended Application
Begin by confirming whether the material is intended for dietary supplements, fortified foods, premix manufacturing or another formulation system. The intended use affects the required specification, testing scope, packaging arrangement and supporting documents.
Confirm the Assay and Standard
Confirm the required assay, applicable compendial standard or customer specification before requesting a quotation. General descriptions such as food grade or pharmaceutical grade should be supported by clearly defined test items, analytical methods and acceptance limits.
Confirm Market and Documentation Requirements
Provide the destination country and required document package, including any need for COA, SDS/MSDS, TDS, country-of-origin statement or additional quality declarations. This allows the specification and document availability to be checked before order placement.
Provide Complete RFQ Information
For accurate product confirmation, provide the intended application, required specification, expected quantity, preferred packing, destination country and required documents.
High-Purity Cyanocobalamin vs Vitamin B12 1% Premix
High-Purity Cyanocobalamin Powder
High-purity cyanocobalamin powder is suitable for manufacturers with accurate low-dose weighing, controlled dilution and validated premixing procedures. It provides direct control over the vitamin B12 input and is commonly selected for supplement manufacturing, customized premixes and projects requiring a high-potency raw material.
Vitamin B12 1% Premix
Vitamin B12 1% premix may be more practical where easier weighing, improved distribution uniformity and larger-batch handling are important. Carrier type, potency, intended application and target standard should be confirmed before selection.
Internal link anchor: Vitamin B12 1% Premix
Technical & Formulation Notes
Technical Notes
Cyanocobalamin is generally evaluated as a commercially practical vitamin B12 form for broad-market supplement, food-fortification, premix and specification-driven formulation projects. Technical review normally focuses on assay basis, identification, related substances, batch consistency, applicable standard and documentation scope rather than consumer-facing dosage or health claims.
Manufacturing & Process
Commercial cyanocobalamin production involves controlled upstream production followed by recovery, purification, crystallization, drying and final quality testing. The exact manufacturing route, process statement, production origin and available supporting documents depend on the selected manufacturer and can be reviewed during supplier qualification where required.
Compatibility / Formulation Notes
For Tablets and Capsules
Cyanocobalamin is normally used at a relatively low inclusion level, so accurate weighing and suitable premixing are important before final blending. A controlled dilution or premix step may be required where direct low-dose addition creates a risk of uneven distribution.
For Gummies and Powder Blends
Mixing sequence, dispersion uniformity, moisture exposure and light protection should be reviewed during formulation trials. The ingredient should be incorporated through a suitable process that supports consistent distribution without unnecessary exposure during production.
For Fortified Foods and Beverage Premixes
Processing temperature, pH, light exposure and compatibility with companion ingredients should be evaluated in the customer’s actual formulation system. Raw-material assay alone does not confirm stability or performance in the finished food or beverage matrix.
Production Handling
Unnecessary exposure to direct light, moisture and excessive heat should be minimized during sampling, weighing and manufacturing. The selected pack size should match the expected consumption rate to reduce repeated opening and prolonged exposure.
Pilot Testing
Final compatibility, dosage uniformity and finished-product stability should be confirmed through pilot-scale trials and appropriate finished-product testing before commercial production.
Extended QC & Test Items
Depending on the agreed specification, batch quality review may include identification, appearance, assay, loss on drying or moisture, related substances or impurity profile, residual solvents, elemental impurities or heavy metals, and microbiological limits where applicable. Final test items, analytical methods and acceptance limits are governed by the agreed specification and batch Certificate of Analysis.
Product specifications
| Test | Specification | Method |
|---|---|---|
| Assay (Cyanocobalamin) | 99.0% min | USP / HPLC |
| CAS No. | 68-19-9 | - |
| Appearance | Dark red crystalline powder | Visual |
| Loss on drying | <= 12.0% (typical) | USP |
| Heavy metals | Meets USP limits (as required) | ICP-MS / USP |
| Microbial limits | Meets relevant limits (as required) | USP / ISO |
Storage, Shelf Life & Packaging
Storage
Storage
Store at 2–8°C in tightly sealed, light-protective containers. Protect from moisture, heat, direct sunlight, and unnecessary air exposure during storage and transportation.
Handling Note
Because cyanocobalamin is a high-value and light-sensitive vitamin ingredient, storage control, moisture protection, and package integrity should be maintained throughout warehousing and internal handling.
Shelf Life
Typically 24 months from production date under recommended storage conditions.
Re-test / Expiry
Please refer to the COA for batch-specific retest/expiry date.
After Opening
Use promptly after opening and reseal tightly after each use.
Packaging & Logistics
Standard Packing
To better support light protection, moisture control, and high-value raw-material handling, cyanocobalamin powder is commonly packed in 100 g, 500 g, and 1 kg sealed aluminum tins.
Sample Packing
Small evaluation packs can be arranged for technical review, formulation screening, and sourcing assessment.
Bulk Supply
Commercial supply can be arranged according to the required quantity and shipment plan, with packing format confirmed based on product scope, handling needs, and destination-market requirements.
Logistics & Documents
COA, SDS/MSDS, and TDS/specification sheet can be arranged according to the agreed supply plan. For higher-value vitamin projects, package integrity and light-protection control should be confirmed before shipment.
Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Vitamin B12 Product Selection Support
We support buyers comparing Cyanocobalamin with Methylcobalamin, Hydroxocobalamin, Adenosylcobalamin and Vitamin B12 premix grades, helping them select the appropriate form according to application, formulation requirements and commercial positioning.
Defined Specification Review
Assay, applicable standard, test scope, packing and documentation requirements are reviewed before quotation, helping buyers compare products on the same specification basis rather than relying only on the ingredient name or headline price.
Batch Documentation Support
Batch COA and applicable SDS/MSDS and TDS documents are available for purchasing, quality and technical review. Additional supporting statements can be checked according to the selected manufacturer and project requirements.
Export Supply Coordination
Samples, commercial packing, export documentation and international shipping options can be coordinated according to order quantity, destination and product-handling requirements.
FAQ
What assay or specification do you supply?
Cyanocobalamin powder is commonly available at 99.0% minimum assay with USP-aligned or customer-agreed specifications. Final assay limits, test items and analytical methods are confirmed against the selected specification and batch COA.
What is the difference between Cyanocobalamin and Methylcobalamin?
Cyanocobalamin is commonly selected for broad-market products where established commercial use, supply practicality and cost efficiency are important. Methylcobalamin is more commonly associated with premium active-form positioning. The appropriate choice depends on the finished-product concept, formulation requirements and target market.
What dosage forms can Cyanocobalamin Powder be used in?
Cyanocobalamin powder is commonly evaluated for tablets, capsules, gummies, powder blends, vitamin premixes and fortified foods. Final suitability depends on dosage level, processing conditions, formulation compatibility and finished-product requirements.
Should I choose high-purity Cyanocobalamin or Vitamin B12 1% Premix?
High-purity cyanocobalamin is suitable for manufacturers with accurate low-dose weighing and controlled premixing procedures. Vitamin B12 1% premix may be more practical where easier dosing and improved distribution uniformity are the main priorities.
Can you provide samples and documents?
Yes. Evaluation samples can be arranged, and batch COA, SDS/MSDS and TDS or specification sheets are available. Additional statements depend on the selected product, manufacturer and project requirements.
What information is required for a quotation?
Please provide the intended application, required assay or standard, expected quantity, preferred packing, destination country and required documents. This information allows us to confirm product suitability, stock status, lead time, packing and shipping options.
Need more answers?
Explore our full FAQ library for documentation, compliance, shipping, and ordering guidelines.