High Molecular Weight Hyaluronic Acid
Lifeworth supplies high molecular weight hyaluronic acid, commonly supplied as high molecular weight sodium hyaluronate powder, for cosmetic manufacturers and formulation developers.
High molecular weight sodium hyaluronate is selected when formulators require higher viscosity contribution, texture control and specific formulation characteristics in skincare systems.
We provide technical documentation including COA, TDS and SDS/MSDS to support international B2B ingredient evaluation and bulk purchasing.
• High molecular weight sodium hyaluronate powder for cosmetic formulation projects.
• Suitable for formulations requiring viscosity contribution and texture control.
• Controlled molecular weight specifications for consistent product development.
• Batch COA, TDS and SDS/MSDS documentation available.
• Bulk supply support for international cosmetic ingredient buyers.
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.

Quick Specs
Identity
INCI Name
Alias
CAS Number
Molecular Formula
Molecular Weight
Quality
Assay
Grade
Standards
Assay Method
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
High Molecular Weight Hyaluronic Acid (Sodium Hyaluronate) is a specialized ingredient grade selected by formulators who require controlled molecular weight characteristics for cosmetic applications.
Molecular weight is one of the key factors affecting sodium hyaluronate formulation behavior. High molecular weight grades are commonly considered when formulators require higher viscosity contribution, texture enhancement and specific sensory characteristics in skincare systems.
Lifeworth supplies high molecular weight sodium hyaluronate powder with technical specifications and documentation support for cosmetic manufacturers and international ingredient buyers.
For customers looking for general bulk sodium hyaluronate supply with multiple molecular weight options, please refer to our Hyaluronic Acid Bulk product page.
For lightweight cosmetic formulations requiring different molecular weight characteristics, please explore our Low Molecular Weight Hyaluronic Acid product.
For advanced cosmetic formulation systems using modified HA ingredients, please refer to our Sodium Hyaluronate Crosspolymer.

Applications
Cream and Gel Formulations:
High molecular weight sodium hyaluronate is commonly selected for cream and gel formulations where viscosity contribution and texture characteristics are important.
Rich Texture Skincare Systems:
Suitable for skincare products requiring a more substantial sensory profile and controlled formulation structure.
Advanced Cosmetic Formulations:
Used by cosmetic developers designing customized formulations where molecular weight selection supports specific product characteristics.
How to Choose the Right Grade / Form
High Molecular Weight vs Low Molecular Weight Sodium Hyaluronate:
High molecular weight sodium hyaluronate is often selected when formulators require higher viscosity contribution and specific texture characteristics.
Low molecular weight sodium hyaluronate is commonly considered for lightweight cosmetic formulations where different viscosity behavior and formulation flexibility are required.
The appropriate grade should be selected based on:
• Product format
• Desired sensory profile
• Viscosity requirements
• Formulation objectives
• Application category
Technical & Formulation Notes
Technical Notes
Sodium hyaluronate molecular weight is one of the important parameters influencing formulation characteristics.
High molecular weight sodium hyaluronate is selected when formulators require higher viscosity contribution, texture modification and specific formulation behavior compared with lower molecular weight grades.
Product selection should consider:
• Target product format
• Desired viscosity profile
• Texture requirements
• Formula concentration
• Ingredient compatibility
Specifications can be aligned with customer formulation needs before commercial supply.
Manufacturing & Process
Fermentation → purification → molecular weight adjustment → concentration → drying → milling → packaging.
During manufacturing, molecular weight distribution is controlled according to the required specification range.
Quality control procedures ensure batch consistency and specification compliance for cosmetic ingredient applications.
Compatibility / Formulation Notes
Molecular weight selection:
High molecular weight sodium hyaluronate should be selected according to formulation objectives rather than simply choosing the highest available molecular weight.
Key considerations include:
• Desired viscosity profile
• Texture and sensory requirements
• Product format
• Ingredient compatibility
• Final concentration level
For customers comparing different sodium hyaluronate grades, Lifeworth can provide technical information to support grade selection.
Extended QC & Test Items
• Identification
• Assay
• Molecular weight range
• Glucuronic acid content
• Transparency
• pH value
• Protein content
• Loss on drying
• Heavy metals
• Microbiological limits
• Batch traceability
Product specifications
| Test | Specification | Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Identification | Conforms to agreed specification | Per specification |
| Assay | Per agreed specification | Per specification |
| Molecular Weight | High molecular weight range per agreed specification | Per specification |
| Glucuronic Acid | Per agreed specification | Per specification |
| Intrinsic Viscosity | Per agreed specification | Per specification |
| Transparency | Per agreed specification | Per specification |
| pH | Per agreed specification | Per specification |
| Loss on Drying | Per agreed specification | Per specification |
| Protein | Per agreed specification | Per specification |
| Heavy Metals | Per agreed specification | Per specification |
| Microbiological Limits | Per agreed specification | Per specification |
| Documents | COA per batch; SDS/MSDS and TDS available | Reference |
Storage, Shelf Life & Packaging
Storage
Store high molecular weight sodium hyaluronate in a cool, dry, clean, and well-ventilated place.
Keep the packaging tightly sealed after opening and protect the material from moisture, heat, direct sunlight, and strong odors.
Shelf Life
Shelf life should be confirmed according to the agreed specification, molecular weight range, packaging format, and storage condition.
For sourcing and quality review, please refer to the product label, COA, and batch-specific storage recommendation.
Packaging & Logistics
Sample Packing
Small samples can be arranged for dissolution testing, viscosity evaluation, molecular weight comparison, cream or gel formulation testing, and document review before bulk order confirmation.
Bulk Packing
Bulk packing can be supplied in aluminum foil bags, cartons, drums, 25kg drums, or other agreed packaging formats depending on specification, quantity, and shipping requirements.
Logistics & Documents
COA, SDS/MSDS, TDS/spec sheet, packing list, invoice, and shipping documents can be provided according to order requirements.

Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Defined Spec Clarity
We help buyers review molecular weight range, assay basis, intrinsic viscosity, transparency, pH, protein, document scope, and formulation fit before order confirmation.
Customizable Key Target
High molecular weight, ultra-high molecular weight, or custom molecular weight ranges can be discussed according to cream, gel, mask, serum, or skincare formulation requirements.
Batch Documentation Support
COA, SDS/MSDS, TDS/spec sheet, and other sourcing documents can be provided for quality review, supplier approval, and import preparation.
Export-Ready Bulk Supply
Lifeworth supports sample evaluation, specification review, bulk packing arrangement, and export documentation for cosmetic and personal care formulation customers.

FAQ
Q1: What is high molecular weight hyaluronic acid?
A:
High molecular weight hyaluronic acid is commonly supplied as high molecular weight sodium hyaluronate powder with specific molecular weight characteristics for cosmetic formulation applications.
Q2: Why do formulators choose high molecular weight sodium hyaluronate?
A:
Formulators select high molecular weight sodium hyaluronate when they require viscosity contribution, texture control and specific formulation characteristics.
Q3: Is high molecular weight sodium hyaluronate suitable for cosmetic formulations?
A:
Yes. It is commonly used in skincare systems such as creams, gels and other cosmetic formulations where texture and formulation structure are important.
Q4: What documents are available?
A:
COA, TDS and SDS/MSDS are available for technical evaluation and commercial supply discussions.
Q5: Can I request samples before bulk purchasing?
A:
Yes. Samples are available for evaluation before bulk orders.
Need more answers?
Explore our full FAQ library for documentation, compliance, shipping, and ordering guidelines.