Hydroxocobalamin Powder

Hydroxo-form vitamin B12 supplied as Hydroxocobalamin Acetate or Hydroxocobalamin Hydrochloride for specification-led and professional formulation projects.

Lifeworth supplies hydroxocobalamin powder in two commercial salt forms. Buyers should confirm the required identity, assay basis, applicable standard, packaging and destination-market documentation before supplier comparison.

  • Hydroxocobalamin Acetate and Hydrochloride available
  • Salt-specific identity and specification review
  • Batch COA, SDS/MSDS and TDS support
  • Evaluation samples and commercial packing options
  • Export supply for specification-driven projects

Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.

vitamin b12 hydroxocobalamin acetate hydrochloride Chloride

Quick Specs

Identity

INCI Name

hydroxocobalamin

Alias

Hydroxocobalamin (Vitamin B12A)

CAS Number

13422-51-0

Molecular Formula

C62H89CoN13O15P

Molecular Weight

1346.36 g/mol

Quality

Assay

96.0%–102.0%

Grade

Pharm Grade

Standards

BP, USP, EP

Assay Method

HPLC

Handling

Appearance

Dark red crystalline powder

Form

Powder

Solubility

Soluble in water (typical).

Applications

Dietary supplements; nutrition premixes; fortified products (as permitted); pharmaceutical-oriented evaluation (as per buyer requirements).

Commercial Terms

MOQ

MOQ depends on packaging and specification.

Lead Time

3–7 working days for standard items; bulk orders by schedule.

Incoterms

EXW / FOB / CIF / DAP / DDP

Sample

Free sample (shipping charged)

Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.

Product Overview

Hydroxocobalamin powder is a hydroxo-form vitamin B12 raw material supplied commercially in salt forms including Hydroxocobalamin Acetate and Hydroxocobalamin Hydrochloride for professional and specification-driven projects.

It is supplied according to the selected salt form and agreed specification, and buyers usually confirm exact product identity, CAS number, assay basis, applicable standard and document wording before technical or commercial evaluation.

It is commonly reviewed for specialized supplement, professional nutrition and pharmaceutical-oriented formulation projects, with batch COA, technical documents, sample evaluation and bulk supply support available.

 

Hydroxocobalamin USP (Vitamin B12A) Powder

Applications

Specification-Driven Formulation Projects

Hydroxocobalamin is commonly reviewed for projects where the customer already has a defined salt form, CAS number, internal specification or reference COA. These projects require supplier comparison on the basis of exact identity, assay, impurity controls, analytical methods and document wording rather than the general ingredient name alone.

Professional Nutrition Systems

Hydroxocobalamin Acetate or Hydrochloride may be considered for professional nutrition and specialized supplement systems where the selected salt form fits the formulation and documentation strategy. The appropriate product should be confirmed according to the dosage form, intended market and customer-side technical requirements.

Pharmaceutical-Oriented Evaluation

The material may also be evaluated for pharmaceutical-oriented projects requiring clearly defined identity, pharmacopoeial alignment, assay basis, impurity limits and batch documentation. Final suitability must be reviewed by the customer’s technical, quality and regulatory teams, and this page does not provide medical-use or dosage guidance.

Custom Product Development

For projects that have not yet selected Acetate or Hydrochloride, both forms can be compared according to the available specifications, supporting documents, formulation requirements and destination-market expectations. Pilot evaluation should be completed before commercial selection.

How to Choose the Right Grade / Form

Choose the Required Hydroxocobalamin Form

Hydroxocobalamin Acetate

Hydroxocobalamin Acetate is suitable for projects that specifically identify the acetate salt form in the formulation file, current COA, supplier specification or destination-market documentation. Buyers should confirm the exact product name, CAS number, assay basis, applicable standard and required document wording before quotation.

Hydroxocobalamin Hydrochloride

Hydroxocobalamin Hydrochloride is suitable for projects that specifically require the hydrochloride salt form. It should not be treated as automatically interchangeable with Hydroxocobalamin Acetate because identity information, molecular data, assay basis, specification limits and supporting documents may differ.

Selection Principle

The correct salt form should be selected according to the customer’s existing material specification, current COA, formulation requirement, applicable pharmacopoeia or internal standard, destination market and required document wording. When available, buyers should submit the current specification or COA rather than requesting only “Hydroxocobalamin Powder.”

How to Confirm the Right Specification

Confirm the Exact Product Name

Start by confirming whether the required material is Hydroxocobalamin Acetate or Hydroxocobalamin Hydrochloride. The product name, salt form, CAS number and identity shown in the customer specification should match the proposed supplier documents.

Confirm the Assay Basis and Test Limits

Review the assay range, calculation basis, identification method, related substances, loss on drying, residual solvents and elemental impurities according to the project requirements. Quotations should be compared only after confirming that the specifications use the same chemical form and analytical basis.

Confirm the Applicable Standard

Advise whether the project requires a specific pharmacopoeial reference, internal company specification or customer-agreed standard. The available standard must be checked against the selected salt form and manufacturer documentation rather than assumed from the general Hydroxocobalamin name.

Confirm the Document and Market Requirements

Provide the destination country and required documents, including any need for COA, SDS/MSDS, TDS, country-of-origin statement, manufacturing statement or additional quality declarations. This allows document availability to be checked before order placement.

Technical & Formulation Notes

Technical Notes

Hydroxocobalamin is a general hydroxo-form vitamin B12 description, but commercial purchasing should be based on the exact salt form shown on the COA, TDS, SDS and product label. Hydroxocobalamin Acetate and Hydroxocobalamin Hydrochloride should therefore be reviewed as separate material identities rather than treated as one interchangeable specification.

The product is commonly produced through controlled synthesis, purification, drying, and particle-processing steps designed to support consistent identity, appearance, and batch-to-batch quality performance.

For commercial review, process communication is usually linked to standard alignment, impurity control, light-protective packing, and batch consistency rather than over-detailed manufacturing claims unless project-specific technical data are required.

Salt-Form Confirmation

Formulation work should begin only after the exact hydroxocobalamin salt form has been confirmed. Switching between Acetate and Hydrochloride without technical review may affect molecular calculations, dosage conversion, document consistency and finished-product qualification.

For Capsules and Tablets

Hydroxocobalamin is normally used at a relatively low inclusion level, so accurate weighing, suitable dilution and controlled premixing are important before final blending. Content uniformity should be verified through an appropriate sampling and analytical plan.

For Powder Blends and Premixes

Particle distribution, mixing sequence, moisture exposure and compatibility with other vitamins, minerals or carriers should be reviewed during pilot development. A suitable intermediate premix may be required where direct addition creates a segregation or distribution risk.

Processing and Stability

Light exposure, temperature, pH, moisture and companion ingredients should be evaluated in the customer’s actual formulation. Raw-material assay and identity do not alone establish finished-product stability or compatibility.

Pilot Testing

The selected salt form should be tested in the intended dosage form and packaging system before commercial production. Finished-product testing should confirm potency, uniformity, stability and compliance with the customer’s technical requirements.

Typical QC per batch:

  • Assay (UV/TLC as applicable)
  • Identification
  • Appearance
  • Solubility
  • Loss on drying / moisture
  • Related substances / impurities (as required)
  • Heavy metals (as required)
  • Microbial limits (as required)

Product specifications

TestSpecificationMethod
Assay (Hydroxocobalamin)96.0%–102.0% (Typical: 98.4%)USP / UV
CAS No.13422-51-0-
AppearanceDark red crystalline powderVisual
SolubilitySoluble in waterUSP (typical)
Loss on dryingMeets agreed limits (typical)USP
Heavy metalsMeets relevant limits (as required)ICP-MS / USP

Storage, Shelf Life & Packaging

Storage

Storage
Store at 2–8°C in tightly sealed, light-protective containers. Protect from moisture, heat, direct sunlight, and unnecessary air exposure during storage and transportation.

Handling Note
Because hydroxocobalamin is a high-value and light-sensitive vitamin ingredient, storage control, moisture protection, and package integrity should be maintained throughout warehousing and internal handling.

 

Shelf Life

Shelf life should follow the agreed specification and original packing condition. Batch label, storage compliance, and package integrity should be checked before use.

Packaging & Logistics

Standard Packing
To better support light protection, moisture control, and high-value raw-material handling, hydroxocobalamin powder is commonly packed in 100 g, 500 g, and 1 kg sealed aluminum tins.

Sample Packing
Small evaluation packs can be arranged for technical review, formulation screening, and sourcing assessment.

Bulk Supply
Commercial supply can be arranged according to the required quantity and shipment plan, with packing format confirmed based on product scope, handling needs, and destination-market requirements.

Logistics & Documents
COA, SDS/MSDS, and TDS/specification sheet can be arranged according to the agreed supply plan. For higher-value vitamin projects, package integrity and light-protection control should be confirmed before shipment.

Package of vitamin B12

Supply, Documentation & Customization

Documents & Compliance

COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.

Customization & Private Label

Custom packing, private label, and labeling support available depending on product type and order scope.

Commercial Support

Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.

Why Source From Lifeworth

Salt-Form Identification Support

We help buyers distinguish Hydroxocobalamin Acetate from Hydroxocobalamin Hydrochloride and confirm the required identity before quotation, sampling and commercial supply.

Specification Matching

Customer specifications or existing COAs can be reviewed against available product documents to compare salt form, assay basis, quality limits, analytical methods and document wording.

Separate Batch Documentation

Each supplied salt form is supported by its own applicable COA, SDS/MSDS and TDS or specification documents, helping reduce identity and documentation inconsistencies during qualification and import review.

Export Supply Coordination

Samples, commercial packing, labeling, export documents and international shipment options can be coordinated according to the selected salt form, order quantity and destination.

Lifeworth Company Profile

FAQ

Do you supply Hydroxocobalamin Acetate or Hydroxocobalamin Hydrochloride?

We supply both Hydroxocobalamin Acetate and Hydroxocobalamin Hydrochloride, subject to specification and availability. Please state the required salt form when requesting samples, documents or a quotation.

Are Hydroxocobalamin Acetate and Hydroxocobalamin Hydrochloride interchangeable?

They should not be treated as automatically interchangeable. The two forms may differ in product identity, CAS number, molecular information, assay basis, specification limits and document wording. Any substitution should be reviewed by the customer’s technical and quality teams.

How do I confirm the correct salt form?

Check the exact product name, CAS number, current COA, formulation file, applicable standard and destination-market documentation. Sending your existing specification or COA is the most reliable way to confirm the required form.

What pharmacopoeial or quality standards are available?

Available standards depend on the selected salt form and manufacturer. USP, EP, BP or other references should only be confirmed after reviewing the actual specification and batch-document support.

Can you match our current COA or target specification?

Yes. You can provide your current COA or target specification for comparison. We will review identity, assay basis, test items, acceptance limits, methods and documentation before confirming suitability.

Do you supply Hydroxocobalamin Sulphate?

Our current main supply forms are Hydroxocobalamin Acetate and Hydroxocobalamin Hydrochloride. Other salt forms require separate confirmation and should not be assumed to be interchangeable.

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