L-5-Methyltetrahydrofolate Calcium
Lifeworth supplies L-5-Methyltetrahydrofolate Calcium for supplement brands and manufacturers requiring active folate positioning, assay clarity, stability review, batch documentation, sample evaluation, and export-ready bulk packaging.
- L-5-MTHF-Ca powder, CAS 151533-22-1.
- Suitable for prenatal supplements, tablets, capsules, and nutrition blends.
- Assay, isomer form, stability, moisture, and microbiology can be reviewed.
- COA, SDS/MSDS, TDS, specification sheet, and sample support available.
- Bulk supply support for supplement brands, importers, and contract manufacturers.
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.
Quick Specs
Identity
INCI Name
Alias
CAS Number
Molecular Formula
Molecular Weight
Quality
Assay
Grade
Standards
Assay Method
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
L-5-Methyltetrahydrofolate Calcium is an active folate ingredient commonly used in dietary supplements, prenatal nutrition formulas, tablets, capsules, and functional nutrition products. It is usually supplied as a light yellow to yellow calcium salt powder, and buyers often review assay, isomer form, stability, moisture, heavy metals, microbiology, and document support before technical or commercial evaluation. It is commonly considered for prenatal supplements, folate formulas, multivitamins, tablets, capsules, and powder blends, with sample support and batch documentation available for sourcing reference.
Applications
Dietary Supplements
Suitable for capsules, tablets, powder blends, and multivitamin products where an active folate ingredient is required instead of standard folic acid.
Prenatal Nutrition
Commonly reviewed for prenatal supplement formulas where folate form, dosage level, stability, and document support are important.
Functional Nutrition
Can be used in premium nutrition blends, methylation-oriented formulas, and clinical nutrition concepts where active folate positioning is required.
How to Choose the Right Grade / Form
For Tablets and Capsules
Choose a grade with suitable assay, particle size, flowability, stability, and blending behavior for supplement manufacturing.
For Prenatal Formulas
Choose a specification with clear assay basis, isomer form, stability profile, and supporting documents for prenatal nutrition applications.
For Multivitamin Blends
Choose a grade compatible with minerals, vitamins, botanical extracts, and other active ingredients, with moisture and stability reviewed during pilot testing.
Specification Review
Confirm assay basis, L-form identity, stability, moisture, documentation, and market fit before sampling.
Technical & Formulation Notes
Technical Notes
L-5-MTHF Calcium is evaluated mainly by assay basis, isomer form, calcium salt identity, stability, moisture, color, related substances, and suitability for the finished dosage form.
Buyers should distinguish it from ordinary folic acid and confirm whether the product route matches the target supplement concept.
Manufacturing & Process
This ingredient is supplied as a stabilized calcium salt form of L-5-methyltetrahydrofolate for downstream supplement manufacturing.
Commercial specifications can be reviewed according to assay target, isomer requirement, stability profile, particle size, packaging format, and destination-market documentation needs.
Compatibility / Formulation Notes
For capsules and tablets, review particle size, flowability, blending uniformity, excipient compatibility, and dosage accuracy.
For powder blends, confirm moisture control, color impact, stability, and compatibility with vitamins and minerals.
For prenatal formulas, check local labeling requirements, dosage design, active folate positioning, and document support.
For multi-ingredient formulas, test stability with minerals, antioxidants, and other sensitive ingredients.
Store sealed and protected from moisture, heat, light, oxygen exposure, and contamination.
Extended QC & Test Items
Key QC items may include appearance, identification, assay, isomer purity, calcium content if required, moisture, related substances, heavy metals, microbiology, and batch documentation.
Available documents may include COA, SDS/MSDS, TDS, specification sheet, allergen statement, non-GMO statement, and other support documents according to product route and market.
Product specifications
| Test | Specification | Method |
|---|---|---|
| Appearance | Light yellow to yellow powder | Visual |
| Identification | Conforms to agreed specification | HPLC / Per specification |
| Assay | Per agreed specification | HPLC / Per specification |
| Isomer Purity | Per agreed specification | HPLC / Per specification |
| Calcium Content | If required / Per specification | Per specification |
| Moisture | Per agreed specification | Per specification |
| Related Substances | Per agreed specification | HPLC / Per specification |
| Heavy Metals | Per agreed specification | ICP-MS / Per specification |
| Microbiology | Per agreed specification | Per specification |
| Particle Size | Per agreed specification | Sieve / Per specification |
| Packaging | Per agreed packing format | Reference |
| Documents | COA, SDS/MSDS, TDS available | Reference |
Storage, Shelf Life & Packaging
Storage
Store L-5-Methyltetrahydrofolate Calcium in a tightly sealed original container in a cool, dry, and well-ventilated area.
Protect from moisture, heat, light, oxygen exposure, and contamination.
Shelf Life
Typical shelf life is 24 months when stored under recommended conditions in unopened original packaging.
Final shelf life should follow the agreed specification, batch COA, packaging format, and actual storage conditions.
Packaging & Logistics
Sample Packing
Sample packs are available for laboratory evaluation, formulation testing, assay review, and customer approval.
Bulk Packing
Standard bulk packaging can include 1 kg, 5 kg, 10 kg, 20 kg, or 25 kg packing depending on order quantity and stability requirements.
Customization
Assay review, particle size discussion, packaging protection, private label support, and formula-oriented ingredient matching can be discussed.
Logistics & Documents
COA, SDS/MSDS, TDS, specification sheet, allergen statement, non-GMO statement, packing list, and export documents are available.
Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Defined Spec Clarity
We help buyers confirm assay, isomer form, stability, moisture, QC items, and document requirements before sampling or bulk order.
Customizable Key Target
Specifications can be reviewed according to prenatal, multivitamin, capsule, tablet, or powder blend applications.
Batch Documentation Support
COA, SDS/MSDS, TDS, specification sheet, and supporting statements can be provided for customer approval.
Export-Ready Bulk Supply
Lifeworth supports sample evaluation, bulk packaging, export logistics, and long-term supplement ingredient supply.
FAQ
What is L-5-Methyltetrahydrofolate Calcium?
It is an active folate ingredient supplied as a calcium salt powder for supplements, prenatal formulas, tablets, capsules, and nutrition blends.
What is the CAS number?
The CAS number is 151533-22-1.
Is it the same as folic acid?
No. L-5-MTHF Calcium is an active folate form, while folic acid is a different folate ingredient route.
What should buyers check before ordering?
Buyers should review assay, isomer form, moisture, stability, heavy metals, microbiology, document package, and destination-market suitability.
Is it suitable for prenatal formulas?
It can be used in prenatal supplement concepts, but dosage, labeling, regulatory route, and document support should be confirmed by the buyer.
Can Lifeworth provide samples and documents?
Yes. Samples and documents such as COA, SDS/MSDS, TDS, and specification sheet are available.
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