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potassium guaiacolsulfonate usp

Quick Specs

Identity

Quality

Handling

Commercial Terms

MOQ

MOQ depends on packaging and specification.

Lead Time

3–7 working days for standard items; bulk orders by schedule.

Incoterms

EXW / FOB / CIF / DAP / DDP

Sample

Free sample (shipping charged)

Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.

Introduce Potassium guaiacolsulfonate 

Potassium guaiacolsulfonate(Sulfogaiacol )is a pharmaceutical-grade expectorant widely used in cough relief formulations, cold preparations, and respiratory health products. Known for its ability to help loosen thick mucus and improve airway clearance, potassium guaiacolsulfonate has remained a key active ingredient in many over-the-counter (OTC) cough syrups and tablets.

What Is Potassium Guaiacolsulfonate USP?

Potassium guaiacolsulfonate (also known as Potassium guaiacol sulfonate) is a white to yellowish crystalline powder belonging to the class of expectorants. It is the potassium salt of guaiacolsulfonic acid, used primarily to help clear phlegm from the respiratory tract.

USP grade ensures the product meets strict pharmacopeia standards for safety, quality, and purity required in pharmaceutical formulations.

   

How Potassium Guaiacolsulfonate Works

Potassium guaiacolsulfonate is classified as an expectorant, working by:

Increasing respiratory tract secretions

It stimulates mucous membrane secretions in the bronchi.

Reducing mucus viscosity

The compound helps thin and loosen thick phlegm.

Promoting easier coughing

It enhances the expulsion of mucus, helping clear airways.

Supporting easier breathing during colds or respiratory infections

Useful in conditions where mucus buildup makes breathing uncomfortable.

 

Key Benefits

1.Effective Expectorant

Helps relieve chest congestion by loosening stubborn mucus.

2.Works Well in Combination Formulas

Often included with other cough and cold ingredients such as:

Dextromethorphan

Antihistamines

Nasal decongestants

Herbal cough actives

 

3.Fast Dissolving

Highly water-soluble, ideal for syrups and liquid medicines.

 

4.USP Safety Standard

Ensures high purity, minimal impurities, and guaranteed pharmaceutical quality.

 

5.Suitable for Various Dosage Forms

Syrups

Tablets

Granules

Capsules

Pediatric cough drops

 

Applications of Potassium Guaiacolsulfonate Powder

Potassium guaiacolsulfonate is widely used in:

  1. Cough Syrups & Expectorant Liquids

The most common application due to its excellent solubility.

  1. Cold and Flu Medications

Included in combination OTC formulations.

  1. Respiratory Support Supplements

Used in formulas aimed at improving mucus clearance.

  1. Veterinary Respiratory Medicines

Also used in pet and livestock respiratory health products.

  1. Pharmaceutical Manufacturing

As an API (active pharmaceutical ingredient) used globally.

 

Specifications (Typical USP Standard)

 

ParameterDescription
Assay≥99%
AppearanceWhite to yellowish powder
IdentificationConforms to USP
Loss on Drying≤0.5%
Heavy Metals≤10 ppm
SolubilityFreely soluble in water

 

Lifeworth — Reliable Supplier of Potassium Guaiacolsulfonate USP

Lifeworth is a professional manufacturer and global supplier of potassium guaiacolsulfonate powder, offering pharmaceutical-grade quality suitable for cough syrups, tablets and respiratory health formulations.Our company has passed the third-party audit and certification such as CQC, SGS, INTERTEK, and obtained cGMP, ISO9001, ISO14001, FSSC22000, ISO45001, BRCGS, KOSHER, HALAL and other international certifications.

We can supply 99% Potassium Guaiacolsulfonate USP powder, our annual production of Potassium Guaiacolsulfonate can exceed 2,800 tons.

We can also supply Potassium Guaiacolsulfonate, USP EP BP JP pure salicylic acid powder, 99% USP pure minoxidil raw powder, 99% bulk pure NMN powder, bulk pure glutathione powder 99%, Adenosine triphosphate powder and Raw pure bulk melatonin powder ect.Our products are exported to more than 60 countries in North America, Europe, Asia, Africa, etc. Our product capacity and quality are stable, the price is very competitive in the market, and our products are favored by customers, we Looking forward to working with you to make progress together.

If you want to buy Potassium Guaiacolsulfonate Powder, you can contact our Lifeworth: sales@naturallifeworth.com, we will give you competitive bulk price and more information, believe us, we will not let you down.

Conclusion

Potassium Guaiacolsulfonate USP is a widely used pharmaceutical expectorant valued for its effectiveness, safety, and compatibility with various cough and cold formulations. Its ability to reduce mucus viscosity and support respiratory comfort makes it an important ingredient in global OTC cough medications.

With strong manufacturing capabilities and USP-grade quality assurance, Lifeworth provides reliable bulk potassium guaiacolsulfonate powder for pharmaceutical companies, contract manufacturers, and respiratory product brands worldwide.

Reference:

https://en.wikipedia.org/wiki/Guaiacolsulfonic_acid

https://www.drugs.com/dosage/guaifenesin-potassium-guaiacolsulfonate.html

Package:

1.1-5kg sample order we can provide aluminum foil bag package.

2.5-10kg order we can provide aluminum foil bag package.

Normally a full packge is 25kg/drum or 25kg/bag or 25kg/carton.

Contacts:

E-Mail: sales@naturallifeworth.com
Mobile: 0086-18292562757
Whatsapp: 0086-18292562757

Product Overview

Applications

Technical & Formulation Notes

Technical Notes

Storage, Shelf Life & Packaging

Storage

Shelf Life

Packaging & Logistics

Supply, Documentation & Customization

Documents & Compliance

COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.

Customization & Private Label

Custom packing, private label, and labeling support available depending on product type and order scope.

Commercial Support

Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.

Why Source From Lifeworth

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