5-HTP Powder
Lifeworth supplies 5-HTP powder for B2B buyers who need a standardized Griffonia seed extract with clear 5-hydroxytryptophan assay, controlled packaging, and document support.
- 5-HTP 98%, 99%, or agreed assay specification can be discussed
- Botanical extract powder from Griffonia simplicifolia seed
- Suitable for capsules, tablets, powder blends, sachets, and functional nutrition formulas
- COA, SDS/MSDS, TDS, and specification documents available for sourcing review
- Sample and bulk supply supported according to assay, packaging, and destination requirements
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.

Quick Specs
Identity
INCI Name
Alias
CAS Number
Quality
Assay
Grade
Standards
Assay Method
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
5-HTP Powder is a standardized botanical extract commonly sourced from Griffonia simplicifolia seed and used in supplement, capsule, tablet, powder blend, and functional nutrition formulation projects.
It is usually supplied as white to off-white powder with 5-HTP 98%, 99%, or agreed assay specification, and buyers often review assay method, botanical source, plant part, impurity profile, residual solvents, packaging, and document scope before technical or commercial evaluation.
It is commonly considered for supplement formulas, sachets, powder blends, and functional nutrition products, with sample support and batch documents available for sourcing reference.

Applications
Dietary Supplements
5-HTP powder is commonly used in capsule and tablet supplement projects where buyers need a standardized botanical extract with defined 5-hydroxytryptophan assay. It is suitable for supplement formulas that require clear botanical source, assay consistency, and document support.
Powder Blends and Sachets
For sachets, stick packs, and powder blends, 5-HTP powder may be selected when the formula requires a standardized extract in a dry powder system. Taste profile, solubility behavior, flowability, and compatibility with other ingredients should be tested during pilot development.
Functional Nutrition Formulas
5-HTP powder can be considered for functional nutrition concepts where standardized botanical ingredients are part of the formula design. Buyers should confirm dosage design, market suitability, taste impact, and regulatory expectations before commercial use.
Botanical Extract Formulations
For botanical blend projects, 5-HTP powder should be evaluated together with other plant extracts, vitamins, amino acids, minerals, or functional ingredients. Compatibility, stability, and document scope should be reviewed before bulk procurement.
How to Choose the Right Grade / Form
For standard supplement products
Recommended direction: 5-HTP 98% or 99%
Why: High assay 5-HTP powder is commonly selected for capsules, tablets, and supplement blends requiring defined active content.
For clean botanical positioning
Recommended direction: Griffonia simplicifolia seed extract
Why: Buyers who need natural botanical positioning should confirm source, plant part, extraction route, and document support.
For powder blend applications
Recommended direction: specification matched to blending and taste requirements
Why: Powder formulas should be evaluated for taste profile, flowability, solubility behavior, and compatibility with other ingredients.
For regulated markets
Recommended direction: buyer-defined specification and document package
Why: Different destination markets may require specific test limits, label review, and compliance documents before commercial use.
Confirm assay method
5-HTP powder is usually reviewed by HPLC assay, such as 98%, 99%, or agreed specification. Buyers should confirm the test method and COA format before comparing offers.
Confirm botanical source
Natural 5-HTP is commonly sourced from Griffonia simplicifolia seed. Buyers should confirm source, plant part, extraction route, and available documents before quotation.
Confirm safety and compliance requirements
5-HTP products may be regulated differently depending on country, dosage form, and final product positioning. Buyers should review destination-market requirements and internal compliance rules before bulk purchase.
Technical & Formulation Notes
Technical Notes
Technical Notes
5-HTP powder is mainly evaluated by 5-hydroxytryptophan assay, botanical source, plant part, appearance, identification, impurity profile, residual solvents, heavy metals, and microbiological quality. Buyers should confirm whether the product is natural Griffonia seed extract, synthetic route, or buyer-defined specification before comparing quotations.
Manufacturing & Process
Manufacturing & Process
Natural 5-HTP powder is commonly produced from Griffonia simplicifolia seed through extraction, concentration, purification, drying, milling, and sieving steps according to target assay. Process control focuses on assay, impurity profile, residual solvent control, color, moisture, particle behavior, and batch-to-batch consistency.
Compatibility / Formulation Notes
For capsules and tablets, 5-HTP powder should be evaluated for assay, particle behavior, flowability, excipient compatibility, and moisture sensitivity.
For powder blends and sachets, taste, solubility behavior, blending uniformity, and compatibility with vitamins, minerals, amino acids, and botanical extracts should be tested.
For functional nutrition formulas, the buyer should confirm dosage design, regulatory suitability, flavor impact, and stability in the final product.
For botanical blends, compatibility with other extracts, amino acids, minerals, and functional ingredients should be checked during pilot development.
During storage and handling, 5-HTP powder should be protected from moisture, heat, strong light, oxidizing agents, and prolonged open-air exposure.
Extended QC & Test Items
Extended QC & Test Items
Common review items include appearance, identification, assay, loss on drying, residue on ignition, heavy metals, pesticide residues, residual solvents, microbiology, and batch documentation. Additional tests can be discussed according to destination market, final application, and buyer specification requirements.
Product specifications
| Test | Specification | Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Identification | Conforms to agreed specification | HPLC / TLC / Per specification |
| Assay | 5-HTP 98% / 99% or agreed specification | HPLC / Per specification |
| Source | Griffonia simplicifolia seed | Reference |
| Plant Part | Seed | Reference |
| Loss on Drying | Per agreed specification | Per specification |
| Residue on Ignition | Per agreed specification | Per specification |
| Heavy Metals | Per agreed specification | Per specification |
| Lead | Per agreed specification | Per specification |
| Arsenic | Per agreed specification | Per specification |
| Cadmium | Per agreed specification | Per specification |
| Mercury | Per agreed specification | Per specification |
| Pesticide Residues | Per agreed specification | Per specification |
| Residual Solvents | Per agreed specification | Per specification |
| Total Plate Count | Per agreed specification | Per specification |
| Yeast & Mold | Per agreed specification | Per specification |
| E. coli | Negative or per specification | Per specification |
| Salmonella | Negative or per specification | Per specification |
| Documents | COA, SDS/MSDS, TDS available | Reference |
Storage, Shelf Life & Packaging
Storage
Store 5-HTP powder in a tightly sealed original container in a cool, dry, and well-ventilated place. Keep away from moisture, heat, strong light, oxidizing agents, contamination risk, and strong odors. After opening, reseal the package immediately and handle under clean, dry conditions.
Shelf Life
Shelf life is usually reviewed according to the agreed specification, packaging, and storage conditions. Under proper storage, 5-HTP powder should be evaluated based on batch COA and supplier documentation. Buyers should avoid prolonged exposure to humidity, heat, air, and unsuitable handling conditions.
Packaging & Logistics
Sample Packing
Small samples can be arranged for formulation evaluation, assay review, sensory testing, and document confirmation. Sample availability depends on assay, stock status, shipping route, and destination requirements.
Bulk Packing
Bulk packing can be supplied in sealed foil bags, cartons, fiber drums, or customized packaging according to order quantity and specification. Packaging should help protect the material from moisture, light, oxidation, and contamination during storage and transport.
Customization
Assay level, particle size, packaging, document scope, and additional test items can be discussed according to supplement, sachet, tablet, capsule, or functional nutrition project requirements.
Logistics & Documents
COA, SDS/MSDS, TDS, specification sheet, packing information, and other available documents can be provided for buyer review. Export documents can be arranged according to order terms, shipping route, and destination market requirements.

Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Defined spec clarity
We support 5-HTP powder sourcing based on assay, botanical source, plant part, impurity profile, packaging, and document requirements, helping buyers compare suitable specifications before purchase.
Customizable key target
Assay, particle size, packaging, test items, and document scope can be discussed according to supplement, capsule, tablet, sachet, or functional nutrition project needs.
Batch documentation support
COA, SDS/MSDS, TDS, and specification documents are available to support technical evaluation, supplier qualification, and import preparation.
Export-ready bulk supply
Sample and bulk orders can be supported with practical packaging, logistics coordination, and document preparation for international B2B sourcing.

FAQ
What is 5-HTP Powder?
5-HTP Powder is a standardized botanical extract commonly sourced from Griffonia simplicifolia seed and evaluated by 5-hydroxytryptophan assay for supplement and functional nutrition formulation projects.
What assay can you supply?
We can discuss 5-HTP 98%, 99%, or other agreed specifications depending on project requirements, test method, stock status, and buyer requirements.
Is 5-HTP Powder the same as Tryptamine or 5-Methoxytryptamine?
No. 5-HTP, tryptamine, and 5-methoxytryptamine are different compounds with different CAS identities, sourcing logic, and application routes. Buyers should confirm the exact product name, CAS number, assay, and COA before ordering.
Is this product intended for direct medical use?
This page is positioned for B2B raw material and formulation sourcing only. Final product use, dosage, claims, and regulatory compliance should be reviewed by the buyer's technical and regulatory teams.
What documents are available?
COA, SDS/MSDS, TDS, and specification documents are available. Additional documents may depend on assay, source route, destination market, shipping route, and buyer requirements.
How should 5-HTP Powder be stored?
It should be stored in a sealed container in a cool, dry, and light-protected place away from moisture, heat, oxidizing agents, and contamination risk. The package should be resealed quickly after opening.
Need more answers?
Explore our full FAQ library for documentation, compliance, shipping, and ordering guidelines.