R-Alpha Lipoic Acid Tromethamine Salt
Lifeworth supplies R-Alpha Lipoic Acid Tromethamine Salt for technical sourcing, formulation development, supplier replacement, and reference-specification projects that specifically require the tromethamine salt form of R-Alpha Lipoic Acid.
- Defined Tromethamine / Trometamol Salt Identity
- Reference COA / TDS matching support
- R-isomer and salt-form specification review
- Samples available for technical evaluation
- Batch documentation and bulk export supply support
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.
Quick Specs
Identity
INCI Name
Alias
CAS Number
Molecular Formula
Molecular Weight
Quality
Assay
Grade
Standards
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
R-Alpha Lipoic Acid Tromethamine Salt is a defined salt form of R-Alpha Lipoic Acid formed with tromethamine, which may also be referred to as trometamol in pharmaceutical and technical documentation.
This material is different from both free R-Alpha Lipoic Acid and Sodium R-Lipoate. Free R-ALA is the R-isomer in free-acid form, while Sodium R-Lipoate is the sodium salt of R-ALA. R-ALA Tromethamine should therefore be treated as a separate raw-material identity rather than as a general substitute for other R-ALA forms.
In commercial sourcing, this product is usually relevant when an existing formulation, customer specification, technical dossier, reference product, or development project specifically calls for the tromethamine / trometamol salt form.
Applications
Existing Formula or Reference Product
This route may be required when an established formulation, approved raw-material specification, technical dossier, or reference product identifies R-ALA Tromethamine or R-ALA Trometamol as the required ingredient form.
Salt-Form Specific Development
Formulation teams may evaluate R-ALA Tromethamine when a project requires a defined R-ALA salt form rather than free R-ALA or Sodium R-Lipoate.
Pharmaceutical & Technical Formulation Projects
This material may be reviewed in technical or pharmaceutical formulation projects where chemical identity, salt form, R-isomer control, analytical parameters, and batch documentation are part of the qualification process.
Supplier Replacement & Material Matching
For projects replacing an existing supplier, the proposed material should be compared against the current COA, TDS, analytical profile, and approved raw-material specification before sample qualification.
How to Choose the Right Grade / Form
You Already Have a COA or TDS
Review the exact chemical name, CAS number, salt form, assay, R-isomer or optical requirements, specific rotation where applicable, and other critical analytical parameters.
Your Specification Only Says “Stabilized R-ALA”
Do not assume that R-ALA Tromethamine is automatically the required material. Confirm whether the project actually requires Tromethamine salt, Sodium R-Lipoate, or another defined R-ALA form.
You Are Replacing an Existing Raw Material
Provide the current supplier COA, TDS, label, or approved specification so that the salt form and critical quality attributes can be compared before sampling.
You Are Developing a New Formulation
Select the R-ALA form according to formulation objectives, supplier technical data, compatibility, process conditions, and development testing rather than product name alone.
R-ALA Tromethamine vs Other R-ALA Forms
| R-ALA Form | Chemical Route | Typical Selection Basis | Key Confirmation |
|---|---|---|---|
| Free R-Alpha Lipoic Acid | R-isomer free-acid form | When the specification requires free R-ALA | R-isomer identity, assay, analytical method |
| Sodium R-Lipoate / Na R-ALA | Sodium salt of R-ALA | When the formulation specifically requires the sodium salt route | Sodium salt identity, R-isomer requirement, specification |
| R-ALA Tromethamine / Trometamol | Tromethamine salt of R-ALA | When an existing or development specification specifically requires this salt form | Salt-form identity, assay, R-isomer / optical parameters, reference specification |
These R-ALA forms should not be treated as interchangeable without confirming the formulation, technical specification, and applicable analytical requirements.
Technical & Formulation Notes
Technical Notes
Salt-Form Identity
R-ALA Tromethamine should be confirmed as the tromethamine / trometamol salt of R-Alpha Lipoic Acid rather than free R-ALA or Sodium R-Lipoate.
Tromethamine / Trometamol Naming
Technical, pharmaceutical, and supplier documentation may use either “tromethamine” or “trometamol.” The complete chemical identity should be confirmed from the specification rather than relying on naming alone.
R-Isomer Requirement
General chemical purity does not by itself establish the required R-isomer identity. Stereochemical or optical requirements should be reviewed according to the applicable specification and analytical method.
Reference-Specification Matching
For existing products or supplier replacement projects, critical parameters should be compared against the current approved COA, TDS, or raw-material specification before qualification.
Manufacturing & Process
Supplier Change & Process Review
When changing supplier, compare the approved material specification and critical analytical parameters before introducing the new batch into production.
Processing Conditions
Dissolution behavior, concentration, pH, addition sequence, temperature, and other relevant process conditions should be evaluated according to supplier data and the intended formulation.
Pilot-to-Commercial Scale-Up
Laboratory or pilot testing is recommended before commercial scale-up when the supplier, salt form, or processing conditions change.
Compatibility / Formulation Notes
Existing Formulation Matching
Do not replace free R-ALA, Sodium R-Lipoate, or another R-ALA form with Tromethamine salt without technical evaluation.
Dissolution & Incorporation
Dissolution behavior, concentration, pH, addition sequence, and processing conditions should be evaluated according to supplier data and the intended formulation.
Compatibility Evaluation
Compatibility should be assessed within the complete formulation system, particularly when the product is used with other active ingredients, excipients, acids, bases, or minerals.
Pilot Evaluation
Laboratory or pilot testing is recommended before commercial scale-up when changing supplier, salt form, or formulation conditions.
Extended QC & Test Items
Chemical Identity
Testing should confirm the required R-Alpha Lipoic Acid Tromethamine / Trometamol salt form.
Assay / Purity
Assay or chemical purity should be reviewed against the agreed specification and applicable analytical method.
R-Isomer / Optical Purity
Where applicable, the required R-isomer or optical purity should be confirmed independently from general assay.
Specific Rotation
Specific rotation may be an important identity or stereochemical parameter where included in the applicable specification.
Related Substances & Impurities
Related substances and other impurity controls should be evaluated according to the agreed specification and analytical method.
Residual Solvents & Moisture
Residual solvents, loss on drying, moisture-related parameters, or other process-related quality controls may be reviewed where applicable.
Batch-to-Batch Matching
For approved or reference-specification projects, commercial batches should be reviewed against the agreed critical quality parameters to support consistent qualification.
Reference COA / TDS Matching
For this product, reference-document matching can be more useful than selecting material by product name alone.
If you already use R-ALA Tromethamine from another supplier, provide the current COA, TDS, specification, or ingredient label where available. Key items such as chemical identity, CAS number, assay, R-isomer or optical requirements, specific rotation, impurity controls, and physical characteristics can then be compared before arranging a sample.
This approach is particularly useful for supplier replacement, technical qualification, and established formulation projects.
Product specifications
| Test | Specification | Method |
|---|---|---|
| Chemical Identity | R-Alpha Lipoic Acid Tromethamine / Trometamol Salt | According to agreed specification |
| Appearance | According to applicable product specification | Per specification |
| Assay / Purity | According to agreed specification | Applicable analytical method |
| R-Isomer / Optical Purity | According to agreed specification where required | Applicable stereochemical / optical method |
| Specific Rotation | According to agreed specification where applicable | Applicable specification method |
| Related Substances / Impurities | According to agreed specification | Applicable analytical method |
| Documents | COA per batch; SDS/MSDS and TDS available | Reference |
Storage, Shelf Life & Packaging
Storage
Store according to the applicable supplier specification in sealed packaging and protect the material from unsuitable heat, moisture, and prolonged exposure during handling and storage.
Shelf Life
Shelf life should follow the applicable product specification and original sealed packaging conditions.
Packaging & Logistics
Technical Sample Evaluation
Samples can be arranged for analytical, formulation, compatibility, or supplier-qualification testing before commercial purchasing.
Specification Confirmation
The required chemical form, analytical parameters, and document requirements should be confirmed before quotation where the project follows an existing technical specification.
Batch Documentation
Batch COA, SDS/MSDS, TDS, and available quality or technical documents can be supplied according to the selected specification.
Bulk Supply & Export Support
Commercial quantities, export packaging, labeling, and shipment arrangements can be coordinated according to project requirements and destination.
Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Reference Specification Matching
Support for comparing an existing COA, TDS, approved raw-material specification, or current supplier material against the available R-ALA Tromethamine product.
Salt-Form Confirmation
We help distinguish R-ALA Tromethamine from free R-ALA, Sodium R-Lipoate, and other R-ALA forms before sampling or commercial quotation.
Analytical Requirement Review
Project requirements such as assay, R-isomer or optical identity, specific rotation, impurity controls, and other relevant parameters can be reviewed against available technical documentation.
Sample Before Qualification
Samples can be arranged for analytical or formulation evaluation before supplier approval and scale-up.
Commercial & Export Coordination
Support is available for bulk supply, batch documents, packaging, labeling, and international shipment planning.
FAQ
1) What is R-Alpha Lipoic Acid Tromethamine?
It is commonly supplied as a defined powder raw material under agreed commercial specifications for B2B sourcing projects.
2) What applications is this material commonly reviewed for?
It is commonly reviewed for dietary supplements, capsules, tablets, sachets, powder blends, and functional nutrition formulations.
3) Is sample support available?
Yes. Sample support can usually be arranged for product evaluation, pilot testing, and supplier qualification.
4) What documents are available?
COA per batch, SDS/MSDS, and TDS/specification sheet can be prepared according to the agreed product scope.
5) What should buyers confirm before placing an order?
Buyers should confirm the specification, packaging format, quantity, lead time, shipping terms, and required documentation before bulk purchase.
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