phylloquinone vitamin k1

What Is Vitamin K1?

Vitamin K1, also known as phylloquinone, it is a fat-soluble vitamin that plays a vital role in blood coagulation, bone metabolism, and cardiovascular health. It is one of the two main types of vitamin K, the other being vitamin K2 (menaquinone).

Vitamin K1 is primarily found in green leafy vegetables like spinach, kale, and broccoli, and is also produced through synthetic and fermentation processes for use in nutraceuticals, pharmaceuticals, and cosmetics.

Commercially, vitamin K1 is available in two major forms:

Vitamin K1 Powder – used in capsules, tablets, and dry-blend formulations.

Vitamin K1 Oil – used in softgel capsules, emulsions, and cosmetic formulations.

Both forms have distinct advantages depending on formulation requirements and solubility needs.

Vitamin K1 Powder vs Vitamin K1 Oil

Both forms deliver phylloquinone, the biologically active molecule, but the choice between powder and oil depends on the end product. For instance, supplement makers often choose powder for easy blending, while cosmetic or softgel manufacturers prefer oil for lipid-based systems.

Production Process of Vitamin K1 Powder and Oil

1. Natural Extraction

Vitamin K1 can be extracted from green plants or alfalfa using organic solvents, followed by purification and crystallization. Natural extraction yields high-quality vitamin K1 suitable for clean-label and organic formulations.

2. Synthetic Production

For large-scale commercial use, vitamin K1 is often synthetically produced through a multi-step chemical synthesis involving phytol and menadione derivatives. This ensures consistent quality and purity for pharmaceutical applications.

3. Microencapsulation (for Powder Form)

To enhance the stability and dispersibility of vitamin K1 powder, microencapsulation technology is applied. The oil form of vitamin K1 is encapsulated into a dry powder matrix using carriers like maltodextrin or gum arabic, creating a free-flowing powder suitable for tablets and premixes.

Functions and Benefits of Vitamin K1

1. Blood Clotting and Coagulation

Vitamin K1 is a key cofactor in the synthesis of prothrombin (factor II) and other clotting factors (VII, IX, and X). Adequate vitamin K1 ensures normal blood coagulation and prevents excessive bleeding or bruising.

2. Bone Metabolism

Vitamin K1 activates osteocalcin, a protein responsible for binding calcium in bones. This helps maintain bone density and strength, reducing the risk of osteoporosis and fractures, especially in aging populations.

3. Heart and Vascular Health

Vitamin K1 prevents the calcification of arteries by activating matrix Gla protein (MGP). This supports cardiovascular health by keeping calcium in the bones rather than in the arteries, thereby reducing the risk of atherosclerosis.

4. Liver and Detoxification

The liver relies on vitamin K1 to produce key proteins that regulate blood clotting and detoxification processes. It’s often used clinically to counteract vitamin K deficiency or the effects of anticoagulant drugs.

5. Skin and Cosmetic Benefits

Vitamin K1 oil is increasingly popular in cosmetics for its anti-inflammatory and restorative properties. It helps reduce:

Dark under-eye circles

Spider veins

Redness and bruising

Post-surgery discoloration

It also promotes skin regeneration, making it an effective ingredient in high-end skincare formulations.

Applications of Vitamin K1

1. Dietary Supplements

Vitamin K1 powder and oil are widely used in:

Capsules, tablets, and softgels

Multivitamin blends

Bone and cardiovascular support formulas

Often combined with vitamin D3 and calcium for synergistic effects.

2. Pharmaceutical Formulations

Pharmaceutical-grade vitamin K1 is used to:

Treat bleeding disorders due to deficiency or anticoagulant overdose.

Support newborn health, as infants are at higher risk of deficiency.

Formulate injectable vitamin K1 preparations for emergency use.

3. Cosmetics and Personal Care

Vitamin K1 oil is utilized in:

Eye creams, anti-bruising gels, and post-laser care products.

Brightening and firming serums for sensitive or damaged skin.

Anti-aging creams where it enhances skin tone and elasticity.

4. Functional Foods and Beverages

Microencapsulated vitamin K1 powder is added to:

Nutritional drinks and shakes

Infant formulas

Fortified dairy and cereal products

This helps ensure adequate intake, especially for those with low vegetable consumption.

Recommended Dosage

In supplement formulations, vitamin K1 powder or oil typically provides 50–200 µg per serving, depending on the product’s health focus.

Quality Specification

Where To Buy Vitamin k1？

Lifeworth is a leading Chinese manufacturer and supplier of Vitamin K1 products, offering premium-quality phylloquinone ingredients to global clients in the nutraceutical, pharmaceutical, and cosmetic industries. Our company occupies approximately 30,000 square meters and has passed third-party audits and certifications such as CQC, SGS, and INTERTEK. We also hold international certifications such as cGMP, ISO9001, ISO14001, FSSC22000, ISO45001, BRCGS, KOSHER, and HALAL.

We can supply 99% pure vitamin K1 oil, vitamin K1 microencapsulated powder, and vitamin K1 powder, with an annual output of more than 9,500 tons.

In addition to vitamin K1 products, our main products also include vitamin K2MK4, vitamin K2MK7, vitamin A, vitamin D2, vitamin D3 products, natural plant alcohol, chlorophyll paste, sodium copper chlorophyllin, and Magnesium sodium chlorophyllin ect., our all the products meet with USP BP EP standard. Our product has been exported to more than 60 countries including Germany, Japan, the United States, France, and South Korea. It has established long-term and stable cooperative relationships with many customers, and its product quality is deeply trusted by customers.

If you want to buy vitamin K1, you can contact our Lifeworth: sales@naturallifeworth.com, we will give you competitive bulk price and more information, believe us, we will not let you down.

Conclusion

Vitamin K1 powder and oil are essential, versatile ingredients widely used in nutritional supplements, pharmaceuticals, and cosmetics. From supporting blood coagulation and bone health to promoting skin recovery and cardiovascular protection, vitamin K1 remains a cornerstone nutrient for overall wellness.

As a professional Vitamin K1 manufacturer and supplier, Lifeworth provides high-purity, stable, and customizable Vitamin K1 ingredients to meet global industrial demands.

If you’re looking for the best Vitamin K1 supplier, pure phylloquinone powder and oil, or simply want to buy Vitamin K1 in bulk, Lifeworth offers reliable quality, technical support, and long-term partnership opportunities.

Reference:

https://www.ncbi.nlm.nih.gov/books/NBK557622/

https://www.webmd.com/drugs/2/drug-4814/phytonadione-vitamin-k1-injection/details

https://en.wikipedia.org/wiki/Phytomenadione

https://www.drugs.com/pro/vitamin-k1.html

https://go.drugbank.com/drugs/DB01022

https://pubmed.ncbi.nlm.nih.gov/32491554/

Package:

1. The sample package is 50g/bag.
2. Powder form:25kg/drum
3. Liquid form:1Kg/aluminum can ,5Kg/aluminum can

Contacts:

E-Mail: sales@naturallifeworth.com
Mobile: 0086-18292562757
Whatsapp: 0086-18292562757