Water-Soluble Silymarin
Lifeworth supplies Water-Soluble Silymarin based on a water-soluble silymarin meglumine system, with a typical specification of ≥40% by UV. It is designed for formulations where conventional Silymarin 80% has insufficient water solubility.
- Water-soluble silymarin powder
- Silymarin Meglumine ≥40% by UV
- Suitable for drink powders, sachets, and liquid systems
- Improved water solubility versus conventional Silymarin 80%
- COA / SDS / TDS and sample support
Tell us your application, target specification, and destination market so we can support grade selection, documentation review, and packaging recommendations.

Quick Specs
Identity
INCI Name
Alias
Quality
Assay
Grade
Standards
Assay Method
Handling
Appearance
Form
Solubility
Applications
Commercial Terms
MOQ
MOQ depends on packaging and specification.
Lead Time
3–7 working days for standard items; bulk orders by schedule.
Incoterms
EXW / FOB / CIF / DAP / DDP
Sample
Free sample (shipping charged)
Quality & Documents
COA (per batch) • SDS/MSDS • TDS/Spec sheet (on request). Additional statements depend on product and market.
Product Overview
Water-Soluble Silymarin is a water-soluble milk thistle ingredient designed for formulations where conventional silymarin extract has limited aqueous solubility. The product is supplied as a yellow-brown powder and is soluble in water.
This grade is based on a silymarin meglumine system and is typically standardized to Silymarin Meglumine ≥40% by UV. It can be considered for drink powders, sachets, liquid supplements, soluble blends, and other formulations where rapid dissolution or improved water compatibility is required.
Compared with conventional Silymarin 80%, the main selection difference is not only assay level but also formulation behavior. Buyers should therefore review solubility, assay basis, incorporation method, and finished-system requirements together when selecting a suitable milk thistle ingredient.

Applications
Drink Powders & Sachets
Suitable for instant drink powders, sachets, and reconstitution systems where improved water solubility is required compared with conventional silymarin extract. Final dissolution behavior should be confirmed in the complete formulation.
Liquid Supplements
Can be evaluated for liquid supplement systems where a water-soluble milk thistle ingredient is preferred. Compatibility with pH, sweeteners, flavors, preservatives, and other active ingredients should be confirmed during formulation testing.
Soluble Powder Blends
Suitable for soluble premixes and multi-ingredient powder systems. Buyers should review blending uniformity, hygroscopicity, flowability, dissolution behavior, and compatibility with other water-soluble components.
Water-Based Formulations
Can be considered for selected aqueous systems where conventional Silymarin 80% is not suitable because of limited water solubility. Pilot evaluation is recommended to confirm clarity, sedimentation, and overall formulation stability.
How to Choose the Right Grade / Form
Choose by formulation system
Water-Soluble Silymarin is mainly considered for drink powders, sachets, liquid supplements, soluble blends, and other aqueous formulation systems where conventional silymarin has insufficient water solubility. For capsules, tablets, and dry formulations where water solubility is not required, conventional Silymarin 80% may be a more appropriate commercial option.
Choose by assay and water-soluble grade
This product route is typically supplied as a silymarin meglumine-based water-soluble grade, with a typical specification of Silymarin Meglumine ≥40% by UV. Buyers should confirm the assay basis, target active level, and agreed specification before comparing materials from different suppliers.
Choose by dissolution and finished-product requirements
For aqueous formulations, buyers should evaluate not only whether the powder dissolves in water, but also dissolution time, clarity, sedimentation, concentration, pH compatibility, and behavior in the complete formulation. These parameters may vary depending on other ingredients and processing conditions.
Choose by existing formulation or reference specification
For replacement projects, providing the current COA, specification, or formulation requirements is usually the most reliable way to evaluate technical comparability. Sample testing is recommended when the finished product has defined requirements for clarity, dissolution, stability, or sensory performance.
Technical & Formulation Notes
Technical Notes
Water-Soluble Silymarin should be evaluated differently from conventional standardized Silymarin 80%. The key selection factor is its ability to dissolve in water and perform in aqueous or reconstituted systems, rather than simply matching the assay level of a conventional extract.
For technical evaluation, buyers should confirm the assay basis, water solubility, dissolution behavior, carrier or salt system where applicable, and compatibility with the intended formulation. If the finished product requires a specific clarity, dissolution time, pH range, or sedimentation limit, these requirements should be discussed before sample approval.
Manufacturing & Process
Water-soluble silymarin is produced through a formulation or conversion process that improves the aqueous solubility of conventional silymarin. In this product route, meglumine is used to form a more water-soluble silymarin system.
The final powder should be evaluated according to assay, water solubility, moisture, appearance, and formulation performance. Buyers with specific dissolution, clarity, or processing requirements should confirm these parameters before commercial scale-up.
Compatibility / Formulation Notes
For drink powders and sachets
Evaluate dissolution time, taste impact, color, sedimentation, and compatibility with sweeteners, acids, flavors, and other soluble ingredients.
For liquid supplements
Review pH compatibility, clarity, precipitation risk, preservative system, and stability during storage. Pilot testing should be completed in the final liquid base.
For soluble powder blends
Review flowability, hygroscopicity, blending uniformity, and moisture sensitivity during production and storage.
For capsules and tablets
Water-soluble silymarin can technically be used in solid dosage forms, but conventional standardized Silymarin 80% may be more commercially appropriate when water solubility is not required.
Storage / handling notes
Protect from moisture, heat, and direct light. Because water-soluble formulations may be more moisture-sensitive, keep the package tightly sealed after opening and minimize prolonged exposure to humid conditions.
Extended QC & Test Items
Common review items may include appearance, assay basis, solubility or dispersion-related characteristics, moisture, particle behavior, heavy metals, microbiological indicators, and other agreed specification items.
Final QC scope should follow the selected route and destination-market requirements.
Product specifications
| Test | Specification | Method |
|---|---|---|
| Appearance | Yellow to yellow-brown powder | Visual |
| Assay | Water-soluble silymarin or agreed specification | Per agreed method |
| Source | Milk thistle extract | Reference |
| Solubility / Dispersion | Per agreed specification | Per specification |
| Loss on Drying | Per agreed specification | Per specification |
| Particle Size | Per agreed specification | Sieve / per specification |
| Heavy Metals | Per agreed specification | Per specification |
| Microbiological Limits | Per agreed specification | Per specification |
| Bulk Density / Handling | Per agreed specification | Per specification |
| Documents | COA per batch; SDS/MSDS and TDS available | Reference |
Storage, Shelf Life & Packaging
Storage
Store in a cool, dry place in a tightly sealed container.
Protect from moisture, heat, and direct light during storage, handling, and transport.
Shelf Life
Shelf life should follow the agreed specification, original packing condition, and storage environment.
Batch life should be confirmed according to the final commercial specification and storage practice.
Packaging & Logistics
Sample Packing
Small evaluation packs can be discussed for specification review, pilot testing, and internal approval.
Bulk Packing
Standard bulk export packing can be arranged according to product type, order quantity, and shipping route.
Logistics & Documents
Commercial support may include COA, MSDS / SDS, TDS, packing confirmation, and shipment coordination according to the selected order plan.

Supply, Documentation & Customization
Documents & Compliance
COA, SDS/MSDS, and TDS/spec sheet available based on product and market requirements.
Customization & Private Label
Custom packing, private label, and labeling support available depending on product type and order scope.
Commercial Support
Sample, lead time, and incoterm options can be discussed according to destination market and supply plan.
Why Source From Lifeworth
Water-Soluble Grade Support
Supply support for water-soluble silymarin grades designed for drink powders, sachets, liquid supplements, and other aqueous formulation systems.
Specification & Solubility Review
Assay basis, water solubility, dissolution requirements, and application-specific performance can be reviewed according to the formulation target.
Batch Documentation Support
COA, SDS, and TDS can be provided for technical evaluation, purchasing review, and supplier qualification.
Sample & Bulk Supply
Samples, 25 kg bulk packing, and export shipment arrangements can be coordinated according to project stage and destination.

FAQ
What is Water-Soluble Silymarin?
Water-Soluble Silymarin is a formulated milk thistle ingredient designed to improve the water solubility of conventional silymarin. This grade is based on a silymarin meglumine system and is typically standardized to ≥40% by UV.
How is Water-Soluble Silymarin different from Silymarin 80%?
Conventional Silymarin 80% has limited water solubility and is commonly used in capsules, tablets, and dry powder formulations. Water-Soluble Silymarin is designed for systems where improved dissolution or water compatibility is required.
Is Water-Soluble Silymarin fully soluble in water?
This grade is supplied as a water-soluble powder. Final dissolution, clarity, and sedimentation behavior should still be confirmed in the complete formulation because other ingredients, pH, concentration, and processing conditions can affect the finished system.
What is the typical assay of Water-Soluble Silymarin?
A typical specification is Silymarin Meglumine ≥40% by UV. Final assay requirements should be confirmed against the agreed product specification and batch COA.
Is Water-Soluble Silymarin suitable for beverages and liquid supplements?
It can be evaluated for drink powders, liquid supplements, soluble blends, and other water-based systems. Pilot testing is recommended to confirm dissolution, flavor compatibility, color, pH behavior, and finished-product stability.
Can you provide a sample for formulation testing?
Yes. Samples can be provided for solubility, dissolution, compatibility, and pilot formulation evaluation before commercial ordering.
Need more answers?
Explore our full FAQ library for documentation, compliance, shipping, and ordering guidelines.